Shakira's "La Tortura," a duet with Alejandro Sanz, won song of the year honors at the Latin Grammys, while Argentine rocker Gustavo Cerati had a leading two wins at Thursday night's ceremony, held in this city for the first time.

Shakira, the leading nominee with five, performed the hit song with Sanz in typical gyrating fashion, her chest heaving and hips swaying to the reggaeton-inflected beat. Moments earlier, she was demure as she performed a low-key ballad.

"Thank you for this honor you've given me," Shakira, perhaps the evening's biggest star, said after winning the award, also thanking "the public and to Alejandro, who helped me with this song."

Cerati won two awards: best rock song for "Crimen" and best rock vocal album for "Ahi vamos."

Other winners included Mexican singer/accordion player Julieta Venegas, who was nominated for four awards. She won best alternative album for "Limon y sal" in the pre-televised awards ceremony.

Triple nominee Calle 13 picked up the short music video Grammy for its reggaeton song "Atrevete te, te!"

Under the Mexican regional award categories, Joan Sebastian took away the best banda album award for "Mas alla del sol."