The president of Iran again lashed out at Israel on Friday and said it was "heading toward annihilation," just days after Tehran raised fears about its nuclear activities by saying it successfully enriched uranium for the first time.

President Mahmoud Ahmadinejad called Israel a "permanent threat" to the Middle East that will "soon" be liberated. He also appeared to again question whether the Holocaust really happened.

"Like it or not, the Zionist regime is heading toward annihilation," Ahmadinejad said at the opening of a conference in support of the Palestinians. "The Zionist regime is a rotten, dried tree that will be eliminated by one storm."

Ahmadinejad provoked a world outcry in October when he said Israel should be "wiped off the map."

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